Postdoctoral Fellow, Bone Toxicology - Illinois
Introduction (Program Overview):
To be successful in our goals as an organization, AbbVie needs outstanding individuals willing to challenge themselves to find the best solutions for our patients.
The AbbVie Postdoc Program is one way we are doing just that.
AbbVie Postdoctoral Fellows serve as technical experts who investigate, identify, develop, and optimize new methods / techniques to address critical project needs.
Participants continuously seek to improve existing laboratory methods and processes, read and adapt literature to accomplish assignments, and demonstrate mastery of a broad range of experimental techniques and methods of data analysis.
The Postdoctoral Program is designed for true investigational and experimental research.
Participants will be mentored by renowned industry scientists and collaborators at AbbVie and focus on delivering cutting-edge advancements in Discovery, Development Sciences, and BioPharma.
This enriching training program offers a balance of structured learning and work experience which fosters a learning environment to advance individual development, and offers accessibility to high-level knowledge-building across the drug development continuum.
We are seeking scientists from key U.
S.
-based academic institutions within preferred areas of science for this unique 2-3 year assignment.
Participants will build a solid career foundation in the pharmaceutical industry while building the AbbVie brand as an employer of choice for scientific talent.
Role Overview:
The Preclinical Safety organization is a collaborative team of scientists supporting the development and delivery of innovative therapeutics for patients around the world.
Drug-induced bone effects can impact progression of compounds both in nonclinical and clinical settings.
This is a unique opportunity to join the organization in developing/implementing internal approaches to assessing skeletal toxicities that will provide valuable insight into lesion characterization, mechanism of action, nonclinical to clinical translatability, and monitorability.
The research aims to develop in vitro and in vivo approaches for bone evaluation in rodents, dogs, and nonhuman primates to include but not limited to histology, imaging (micro-CT), biomarkers, and in vitro cellular models.
The Postdoctoral Fellow will report to a mentor with recognized skeletal toxicologic pathology expertise in the Investigative Toxicology and Pathology team, a research group with extensive experience leveraging cutting edge histologic, molecular biology, and imaging tools to address scientific questions impacting drug discovery and development.
In addition, the Postdoc will be advised by a team of scientists with decades of experience in clinical medicine, pathology, toxicology, transcriptomics, molecular biology, histology, imaging, biomarkers, drug metabolism, pharmacokinetics, and statistics.
Full access will be available to molecular biology, histology, cell culture, and imaging capabilities to include micro-CT that can be customized to facilitate development of skeletal toxicity assessment techniques.
Responsibilities:
Efficiently solicit, generate, prioritize, and investigate ideas for developing and applying superior technology to skeletal toxicity assessment.
Proactively seek out new information in the literature with an intent to surpass, not duplicate, previous achievements.
Collaborate with functional and technical experts that will eventually utilize the research to provide AbbVie with a competitive advantage in the discovery and development of new therapeutics.
Independently design and execute experiments, interpret data, troubleshoot, and identify appropriate follow-up strategies.
Maintain a high level of productivity in the laboratory setting.
Effectively present, write and communicate research materials.
Resolve research hurdles by effectively utilizing available information and technical expertise.
Publish research in peer-reviewed journals and present work at scientific conferences aligned with business objectives.
Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
Basic
Qualifications:
PhD in Molecular Biology, Toxicology, Pathology, or related field.
Scientific knowledge of bone biology and experience in the application of bone disease models and/or skeletal medical devices.
Demonstrated ability to bridge multiple disciplines spanning biology, imaging, toxicology, histology (staining of decalcified and undecalcified bone sections with routine H&E, special histochemical, and immunohistochemistry stains), and serum biomarkers through application of relevant techniques.
Interest and ability to contribute outside of primary area of expertise.
Record of scientific initiative and creativity in research or development activities.
Excellent project management skills.
Ability to multitask and work within timelines.
Ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
Demonstrated scientific writing skills and strong verbal communication skills.
Global mindset to thrive in a diverse culture and environment.
Preferred
Qualifications:
Experience with micro-CT imaging instruments and analysis software.
Basic experience in cell culture and in vitro tissue models.
Knowledge of RT-PCR, transcriptomics, proteomics, and in situ hybridization.
Experience with necropsy and tissue trimming of laboratory animals.
Key Leadership Competencies:
Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance.
Learns fast, grasps the essence, and can change course quickly where indicated.
Raises the bar and is never satisfied with the status quo.
Creates a learning environment, open to suggestions and experimentation for improvement.
Embraces the ideas of others, nurtures innovation, and manages to reality.
Recommended Skills Biology Business Planning Creativity Imaging Leadership Medical Material Estimated Salary: $20 to $28 per hour based on qualifications.
To be successful in our goals as an organization, AbbVie needs outstanding individuals willing to challenge themselves to find the best solutions for our patients.
The AbbVie Postdoc Program is one way we are doing just that.
AbbVie Postdoctoral Fellows serve as technical experts who investigate, identify, develop, and optimize new methods / techniques to address critical project needs.
Participants continuously seek to improve existing laboratory methods and processes, read and adapt literature to accomplish assignments, and demonstrate mastery of a broad range of experimental techniques and methods of data analysis.
The Postdoctoral Program is designed for true investigational and experimental research.
Participants will be mentored by renowned industry scientists and collaborators at AbbVie and focus on delivering cutting-edge advancements in Discovery, Development Sciences, and BioPharma.
This enriching training program offers a balance of structured learning and work experience which fosters a learning environment to advance individual development, and offers accessibility to high-level knowledge-building across the drug development continuum.
We are seeking scientists from key U.
S.
-based academic institutions within preferred areas of science for this unique 2-3 year assignment.
Participants will build a solid career foundation in the pharmaceutical industry while building the AbbVie brand as an employer of choice for scientific talent.
Role Overview:
The Preclinical Safety organization is a collaborative team of scientists supporting the development and delivery of innovative therapeutics for patients around the world.
Drug-induced bone effects can impact progression of compounds both in nonclinical and clinical settings.
This is a unique opportunity to join the organization in developing/implementing internal approaches to assessing skeletal toxicities that will provide valuable insight into lesion characterization, mechanism of action, nonclinical to clinical translatability, and monitorability.
The research aims to develop in vitro and in vivo approaches for bone evaluation in rodents, dogs, and nonhuman primates to include but not limited to histology, imaging (micro-CT), biomarkers, and in vitro cellular models.
The Postdoctoral Fellow will report to a mentor with recognized skeletal toxicologic pathology expertise in the Investigative Toxicology and Pathology team, a research group with extensive experience leveraging cutting edge histologic, molecular biology, and imaging tools to address scientific questions impacting drug discovery and development.
In addition, the Postdoc will be advised by a team of scientists with decades of experience in clinical medicine, pathology, toxicology, transcriptomics, molecular biology, histology, imaging, biomarkers, drug metabolism, pharmacokinetics, and statistics.
Full access will be available to molecular biology, histology, cell culture, and imaging capabilities to include micro-CT that can be customized to facilitate development of skeletal toxicity assessment techniques.
Responsibilities:
Efficiently solicit, generate, prioritize, and investigate ideas for developing and applying superior technology to skeletal toxicity assessment.
Proactively seek out new information in the literature with an intent to surpass, not duplicate, previous achievements.
Collaborate with functional and technical experts that will eventually utilize the research to provide AbbVie with a competitive advantage in the discovery and development of new therapeutics.
Independently design and execute experiments, interpret data, troubleshoot, and identify appropriate follow-up strategies.
Maintain a high level of productivity in the laboratory setting.
Effectively present, write and communicate research materials.
Resolve research hurdles by effectively utilizing available information and technical expertise.
Publish research in peer-reviewed journals and present work at scientific conferences aligned with business objectives.
Demonstrate a high degree of responsibility in maintaining scientific standards and safe laboratory practices.
Basic
Qualifications:
PhD in Molecular Biology, Toxicology, Pathology, or related field.
Scientific knowledge of bone biology and experience in the application of bone disease models and/or skeletal medical devices.
Demonstrated ability to bridge multiple disciplines spanning biology, imaging, toxicology, histology (staining of decalcified and undecalcified bone sections with routine H&E, special histochemical, and immunohistochemistry stains), and serum biomarkers through application of relevant techniques.
Interest and ability to contribute outside of primary area of expertise.
Record of scientific initiative and creativity in research or development activities.
Excellent project management skills.
Ability to multitask and work within timelines.
Ability to resolve key project hurdles and assumptions by effectively utilizing available information and technical expertise.
Demonstrated scientific writing skills and strong verbal communication skills.
Global mindset to thrive in a diverse culture and environment.
Preferred
Qualifications:
Experience with micro-CT imaging instruments and analysis software.
Basic experience in cell culture and in vitro tissue models.
Knowledge of RT-PCR, transcriptomics, proteomics, and in situ hybridization.
Experience with necropsy and tissue trimming of laboratory animals.
Key Leadership Competencies:
Builds strong relationships with peers and cross-functionally with partners outside of team to enable higher performance.
Learns fast, grasps the essence, and can change course quickly where indicated.
Raises the bar and is never satisfied with the status quo.
Creates a learning environment, open to suggestions and experimentation for improvement.
Embraces the ideas of others, nurtures innovation, and manages to reality.
Recommended Skills Biology Business Planning Creativity Imaging Leadership Medical Material Estimated Salary: $20 to $28 per hour based on qualifications.
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